Drug Treatment of Esophageal Spasm

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Diffuse Esophageal Spasm

An 82-year-old man was admitted to our hospital due to dysphagia. Barium esophagography showed the esophagus to have a corkscrew appearance (Picture 1). Esophagogastroduodenoscopy also showed similar findings (Picture 2). Given these typical imaging findings, he was diagnosed with diffuse esophageal spasm (DES), although esophageal manometry for a definite diagnosis could not be performed due t...

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A 42-year-old man with history of esophageal strictures and esophageal dilation presented to the emergency department with 12 hours of dysphagia and non-bloody emesis. His symptoms started upon waking and included sharp retrosternal pain during each attempt at swallowing. Dysphagia occurred with both solids and liquid. He denied difficulty initiating swallowing, pain with eating the previous ni...

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Diffuse esophageal spasm is a rare motility disorder. The primary symptoms include dysphagia, and chest pain. There is array of treatments available from medical therapy with nitrates to surgical therapy; Heller myotomy. We present a case of severe Diffuse Esophageal Spasm (DES) that showed one of the highest Distal Contractile Integral (DCI) per manometry. Patient was treated with Botulinum To...

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Of 130 patients diagnosed to have esophageal motility disorders, transformation of diffuse esophageal spasm (DES) into achalasia was identified in one patient. The clinical syndmme of DES was first described by Hamilton Osgood in 1889. It is characterizedby symptoms of substernal chest pain and dysphagia, tertiary contractions on barium swallow and a manometric pattern of frequent simultaneous ...

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ژورنال

عنوان ژورنال: Gastroenterology

سال: 1982

ISSN: 0016-5085

DOI: 10.1016/s0016-5085(82)80173-x